THE CHARCOT-MARIE TYPE OF PROGRESSIVE MUSCULAR ATROPHY

Pathology of peroneal muscular atrophy (Charcot-Marie-Tooth disease).

Four cases of peroneal muscular atrophy (Charcot-Marie-Tooth disease) are described in which observations were made from the necropsy examination of the central nervous system, the peripheral nervous system, and the skeletal muscles. The pattern of nerve degeneration in these various locations is described and the conclusion is drawn that the basis of the disease is a very chronic progressive n...

Progressive Muscular Atrophy

a crack-like ulceration at the junction of the skin and mucous membrane in the two sides of the nose alternately?recurrent attacks of these two complainta during JDecember-January last in a case of progressive muscular atrophy was treated and cured with Bi, plunocaine and sulfanilamide mixed with honey. Was it correct to think that these troubles were of a trophic origin ? As to the P.M.A. the ...

Progressive Muscular Atrophy

Linkage relations of locus for X-borne type of Charcot-Marie-Tooth muscular atrophy and that for Xg blood groups.

The locus for the X-borne type of Charcot-Marie-Tooth muscular atrophy is not close to the Xg locus and probably not within direct measurable distance of it.

The diagnostic dilemma of progressive muscular atrophy.

Progressive muscle atrophy is a rare subtype of motor neuron disease that affects only the lower motor neurons and presents as asymmetrical rapidly progressive muscle weakness, atrophy and normal sensations. The diagnostic electrophysiological findings are denervation potentials in three out of four body segments (bulbar, cervical, thoracic and lumbosacral). The disease is fatal and the managem...